211 CRT responders. Nychtamer dynamicity of Ventricular Repolarization during Biventricular Pacing, vs, Unichamber Pacing

The hemodynamic effect of intrinsic conduction during left ventricular pacing as compared to biventricular pacing.

OBJECTIVES We sought to investigate the effect of intrinsic conduction over the right bundle on the maximum rate of left ventricular pressure rise (LVdP/dt(max)) during left ventricular (LV) pacing compared to biventricular (BiV) pacing. BACKGROUND Simultaneous BiV pacing and LV pacing both improve LV function in patients with heart failure and LV asynchrony. We studied the hemodynamic effect...

Biventricular pacing and transmural dispersion of the repolarization.

In 2003, Medina-Ravell et al. 1 published a study that suggested that biventricular pacing could be arrhythmogenic in a subset of patients because of the reversal of the normal endocardial-to-epicardial activation sequence by left-ventricular epicardial pacing. As epicardial action potentials are briefer than endocardial action potentials, transmural dispersion of the repolarization (TDR) is la...

The effect of ventricular sequential contraction on helical heart during pacing: high septal pacing versus biventricular pacing.

OBJECTIVE To investigate the effect of biventricular and high septal pacing on the normal contraction sequence of the helical ventricular myocardial band, and its impact on left ventricular function. METHODS Ten pigs (25-68 kg) underwent analysis of percent segmental shortening (SS%) by sonomicrometry, with crystals placed along the fiber orientation of the ascending, descending segments, and...

Biventricular pacing and heterogeneity of ventricular repolarization in heart failure patients

OBJECTIVE The aim of our study was to evaluate the effect of cardiac resyncronization therapy (CRT) on QT dispersion (QTd), JT dispersion (JTd) and transmural dispersion of re-polarization (TDR), markers of heterogeneity of ventricular repolarization in a study population with severe heart failure. METHODS AND RESULTS Fifty patients (43 male, 7 female, aged 60.2 ± 3.1 years) suffering from co...

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